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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA3
All Species:
16.67
Human Site:
Y247
Identified Species:
36.67
UniProt:
Q99758
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99758
NP_001080.2
1704
191362
Y247
V
T
I
K
R
F
P
Y
P
P
F
I
A
D
P
Chimpanzee
Pan troglodytes
XP_510744
1704
191477
Y247
V
T
I
K
R
F
P
Y
P
P
F
I
A
D
P
Rhesus Macaque
Macaca mulatta
XP_001085237
1692
190227
Y247
V
T
I
K
R
F
P
Y
P
P
F
I
A
D
P
Dog
Lupus familis
XP_537004
1758
196286
Y298
V
I
A
K
R
F
P
Y
P
P
F
I
S
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R420
1704
191982
F247
V
I
T
K
R
F
P
F
P
P
Y
I
S
D
P
Rat
Rattus norvegicus
Q9ESR9
2434
270910
R430
I
E
P
E
A
L
R
R
G
N
M
S
S
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414701
1641
183766
H237
M
G
L
S
N
W
L
H
W
S
A
W
F
L
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002661144
1343
149621
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
P245
P
I
T
L
R
G
L
P
E
P
R
Y
K
T
S
Sea Urchin
Strong. purpuratus
XP_791165
1668
186656
Y251
I
D
M
Q
R
Y
P
Y
P
P
Y
L
D
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
R257
L
F
S
P
S
V
I
R
M
V
P
F
P
T
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.4
85.1
N.A.
87.9
28.6
N.A.
N.A.
66.3
N.A.
51.4
N.A.
N.A.
N.A.
28.2
44.5
Protein Similarity:
100
99.7
97.2
90.6
N.A.
94.2
43.3
N.A.
N.A.
79.2
N.A.
62
N.A.
N.A.
N.A.
48.4
63.3
P-Site Identity:
100
100
100
80
N.A.
66.6
0
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
13.3
40
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
20
N.A.
N.A.
26.6
N.A.
0
N.A.
N.A.
N.A.
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
0
0
10
0
28
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
10
55
0
% D
% Glu:
0
10
0
10
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
46
0
10
0
0
37
10
10
0
0
% F
% Gly:
0
10
0
0
0
10
0
0
10
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
19
28
28
0
0
0
10
0
0
0
0
46
0
0
0
% I
% Lys:
0
0
0
46
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
10
0
10
10
0
10
19
0
0
0
0
10
0
19
10
% L
% Met:
10
0
10
0
0
0
0
0
10
0
10
0
0
0
10
% M
% Asn:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
10
0
10
10
0
0
55
10
55
64
10
0
10
0
46
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
64
0
10
19
0
0
10
0
0
0
10
% R
% Ser:
0
0
10
10
10
0
0
0
0
10
0
10
28
0
10
% S
% Thr:
0
28
19
0
0
0
0
0
0
0
0
0
0
19
0
% T
% Val:
46
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
10
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
46
0
0
19
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _